Antifungal activity of <em>Cardiospermum halicacabum</em> L. (Sapindaceae) against <em>Trichophyton rubrum</em> occurs through molecular interaction with fungal Hsp90
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چکیده
منابع مشابه
Antifungal efficacy of Capsicum frutescens L. extracts against some prevalent fungal strains associated with groundnut storage
The antifungal potential of aqueous leaf and fruit extracts of Capsicum frutescens against four major fungal strains associated with groundnut storage was evaluated. These seed-borne fungi, namely Aspergillus flavus, A. niger, Penicillium sp. and Rhizopus sp. were isolated by standard agar plate method and identified by macroscopic and microscopic features. The minimum inhibitory concentrations...
متن کاملVegetative storage protein with trypsin inhibitor activity occurs in Sapindus mukorassi, a sapindaceae deciduous tree.
A vegetative storage protein (VSP) with trypsin inhibitor activity in a deciduous tree, Sapindus mukorassi, was characterized by means of sodium dodecyl sulfate-polyacrylamide gel electrophoresis, Western-blot, immuno-histochemical localization, light- and electro-microscopy, together with analysis of proteinase inhibitor activity of the purified VSP in vitro. There were two proteins with molec...
متن کاملAntifungal activity of compounds targeting the Hsp90-calcineurin pathway against various mould species.
OBJECTIVES Invasive mould infections are associated with a high mortality rate and the emergence of MDR moulds is of particular concern. Calcineurin and its chaperone, the heat shock protein 90 (Hsp90), represent an important pathway for fungal virulence that can be targeted at different levels. We investigated the antifungal activity of compounds directly or indirectly targeting the Hsp90-calc...
متن کاملAntifungal activity of Thymus vulgaris L. essential oil and its constituent phytochemicals against Rhizopus oryzae: interaction with ergosterol.
Mucormycoses are emerging infections that have high rates of morbidity and mortality. They show high resistance to antifungal agents, and there is a limited therapeutic arsenal currently available, therefore, there is a great need to give priority to testing therapeutic agents for the treatment of mucormycosis. Along this line, the use of essential oils and phytoconstituents has been emphasized...
متن کاملAntifungal activity of herbal extracts against Malassezia species
Background: Malassezia spp. is an opportunistic dimorphicBasidiomycetous fungi associated with a variety of diseasesincluding dandruff, atopic eczema, pityriasis versicolor, seborrheicdermatitis and folliculitis. It also causes systemic infectionsin immune compromised patients. The aim of this study wasto evaluate the antimicrobial activity of nettle leaves (Urticadioica), colocynths fruits (Ci...
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ژورنال
عنوان ژورنال: Drug Design, Development and Therapy
سال: 2018
ISSN: 1177-8881
DOI: 10.2147/dddt.s155610